The Risk of Colorectal and Other Types of Cancers in Diabetic Patients: A Systematic Review

Introduction: In particular, epidemiological evidence suggests that Increased Type 2 Diabetes is associated with an increased risk of certain specific cancers such as breast cancer, colorectal cancer, liver cancer and pancreatic cancer. Our goal of this systematic review study is to understand the relationship between diabetes and cancer. So this study was done with the goal of determining the risk of colorectal and other types of cancers in diabetic patients.

Materials and Methods: This study is a systematic review that in order to achieve the goal of the study and to improve the accuracy of its study and its comprehension, this integrated overview studies were conducted based on the Broome method. Searching for articles in search engines, authoritative sites and databases Google Scholar, Research gate, Science direct, PubMed, Springer in Persian and English. In the first stage, 39 articles were found. Of these, 10 related articles that have been published over the past 27 years have been reviewed.

Results: In several studies, there was a relationship between different types of cancer and diabetes. One study, conducted by SU luo et al was done, in which 29 metrics including 10 case studies and 19 group studies were included in this meta-analysis. In a combined analysis of all studies, diabetes mellitus was associated with an increased risk of colorectal neoplasm. The risk of colorectal cancer also increased significantly.

Conclusion: In studies that were conducted and reviewed by us, the relationship between diabetes and colorectal cancer and also other types of cancer was quite serious. it is better be done to plan the Ministry of Health in Iran and the World Health Organization to reduce diabetes and cancer.

Keywords: colorectal Cancer, Risk Factor, Type 2 diabetes, Cancer